On the performance and design of BioSequences compared to the Seq language

Introduction In October 2019, a paper was published in Proceedings of the ACM on Programming Languages, introducing a new language for bioinformatics called Seq. In it, the authors rightly recognize that the field of bioinformatics is in need of a high-performance, yet expressive and productive language. They present Seq, a domain specific compiled language, with the user friendliness of Python, the performance of C, and bioinformatics-specific data types and optimisations. As Julians, we consider their goal to be noble and well worth pursuit.